Modern techniques for analyzing biological specimens produce large amounts of data describing gene expression, genome sequences, molecular structures, and molecular interactions. Researchers in the field of bioinformatics develop methods and tools to manage and make meaning of this data. Computational biologists use this data to better understand living systems, while researchers in translational bioinformatics apply these insights to efforts to improve human health.
Bioinformatics and Computational Biology Faculty: Hunter Moseley, Jin Chen, JC Jeong, Mark Ebbert, Sally Ellingson, V K Cody Bumgardner
Projects
- University of Kentucky Markey Cancer Center - Cancer Center Support Grant
- CAREER: Linking Structure, Stability and Protection in Protamine Packaged DNA
- Supplement: Cost Extension - Kentucky Center for Clinical and Translational Science
- CAREER: Developing Biochemoinformatics Tools for Large-Scale Metabolomics Applications
- Lung cancer in Appalachian Kentucky: Deciphering genetic influences
Recent publications and other works
journal article | 2021
McKinnon LM, Miller JB, Whiting MF, Kauwe JSK, Ridge PG
A comprehensive analysis of the phylogenetic signal in ramp sequences in 211 vertebrates
Sci Rep
journal article | 2020
Ellingson SR, Davis B, Allen J
Machine learning and ligand binding predictions: A review of data, methods, and obstacles
Biochimica et biophysica acta. General subjects
journal article | 2020
Jin H, Mitchell JM, Moseley HNB
Metabolites
journal article | 2020
Yao S, Moseley HNB
A chemical interpretation of protein electron density maps in the worldwide protein data bank
PloS one
journal article | 2020
Hinderer EW, Moseley HNB
GOcats: A tool for categorizing Gene Ontology into subgraphs of user-defined concepts
PloS one
journal article | 2020
Powell CD, Kirchoff DC, DeRouchey JE, Moseley HNB
BMC genomics
journal article | 2020
Jin H, Moseley HNB
Robust Moiety Model Selection Using Mass Spectrometry Measured Isotopologues
Metabolites
journal article | 2020
Mitchell JM, Flight RM, Moseley HNB
Deriving Lipid Classification Based on Molecular Formulas
Metabolites
journal article | 2020
Liu S, Liu J, Xie Y, Zhai T, Hinderer EW, Stromberg AJ, Vanderford NL, Kolesar JM, Moseley HNB, Chen L, Liu C, Wang C
Bioinformatics (Oxford, England)
journal article | 2020
Zhong Y, Mohan K, Liu J, Al-Attar A, Lin P, Flight RM, Sun Q, Warmoes MO, Deshpande RR, Liu H, Jung KS, Mitov MI, Lin N, Butterfield DA, Lu S, Liu J, Moseley HNB, Fan TWM, Kleinman ME, Wang QJ
Biochimica et biophysica acta. Molecular basis of disease