2017 KNI Clinical-Translational Research Symposium Abstracts
Cognitive Behavioral
- Cognitive Deficits of Early Aging Are Prevented by Vitamin D3: Underlying Mechanisms from the Hippocampal Transcriptome
- Lead Exposure and Alzheimer's Disease
- Programming Amylin Secretion to Slow AD
- Synaptic Interactions of Aβ(1-42) and Pyroglutamate-modified Aβ(pE3-42) Oligomers
- Vascular-associated Neuroinflammation in Alzheimer's Disease: Differential Effects on Disease Progression modulated by Underlying Amyloid Burden
Epilepsy and Sleep
- A Real-Time Classifier for Closed-Loop Sleep Modulation in Mice
- Delays in Surgical Treatment for Epilepsy and Cerebrovascular Disease: Decades versus Days
- Use of a 30 Minute EEG Over a 2 Hour EEG
- Improvement in Time to Administration of Second Line Antiseizure Medications After Implementation of an Inpatient Status Epilepticus Alert Protocol
- Burden of Arrhythmias in Epilepsy Patients: A Nationwide Inpatient Analysis of 1.4 Million Hospitalizations in the United States
- Noninvasive Seizure Screening in Preclinical Models of Epilepsy
- Predictive Value of Autonomic Variable and Their Correlation With Electrophysiological Signals for Seizures in Refractory Epilepsy
- Reduced Voltage-gated K+ Channel Function in GABAergic NTS Neurons in a Murine Model of Acquired TLE and SUDEP
- Sleep Modulation in Control and Epileptic Mice Through Ambient Temperature Regulation
Other Neurodegenerative
- Antibody-binding Differences in Alpha-Synuclein from Parkinson's Disease and Multiple System Atrophy
- Long Term Intranasal Insulin to Combat Cognitive Decline
- Myosin-15a is Essential Not Only for Proper Elongation but Also for Thickening of Mechanosensory Stereocilia in the Mammalian Auditory Hair Cells
- Novel Applications of MRI Techniques in the Detection of Neuronal Dysfunction before Tangle Pathology in Tau Transgenic Mice
- PERK Inhibition: A Possible Therapeutic Option for Tauopathies
- Signaling and Expression of a Truncated, Constitutively Active Human Insulin Receptor in Hippocampal Neurons
Neurotrauma
- Toward Precision Medicine After SCI: The Genetic Influence of APOE on Respiratory Motor Plasticity
- Inhibition of NADPH Oxidase Attenuates Functional Deficits in Middle-aged Mice After Spinal Cord Injury
- Flubendazole Antimitotic Therapy for Spinal Cord Injury
- Acute Mitochondrial Dysfunction after Mild Traumatic Brain Injury
- Brain Injury-induced Synaptic Reorganization in Hilar Inhibitory Neurons is Differentially Suppressed by Rapamycin
- Characteristics of Sports-Related Concussion in an Adolescent and Young Adult Sample
- Compression Decreases Anatomical and Functional Recovery and Alters Inflammation After Contusive Spinal Cord Injury
- Delayed Frontal Activity in Malingered Traumatic Brain Injuries
- Dysregulated CNS Inflammation After Acute Brain Injury
- Early TGFb Signaling is Required for Tail and Spinal Cord Regeneration in the Mexican Axolotl (Ambystoma mexicanum)
- Effects of Traumatic Brain Injury on miRNA Association with Mitochondria and Intervention Using a Novel Peptide-based Nanoparticle Delivery S
- Inhibition of JNK Signaling Pathway Blocks Tail and Spinal Cord Regeneration in the Mexican Axolotl (Ambystoma mexicanum)
- Insulin-like Growth Factor-1 Overexpression Enhances Neurogenesis and Activates the MTOR Pathway After Moderate TBI
- Mitochondrial Transplantation Following Contusion Spinal Cord Injury
- Myelin Modulates Macrophage Inflammatory Responses After Spinal Cord Injury
- Myeloid-specific Conditional Deletion of p38α MAPK Differentially Regulates the Neuroinflammatory Response to Traumatic Brain Injury
- Pharmacological Inhibition of Oxidative Damage by the Lazaroid U-74389G Improves Cortical Mitochondrial Function Following TBI
- Reduced Frontal Cortical Responses Associated With Cognitive Changes in Individuals with mTBI or PTSD During Working Memory
- Reliability of Five Novel Reaction Time and Cognitive Load Protocols
- The Role of Autoantibodies and B Cells in Traumatic Brain Injury
- Toward Precision Medicine to Treat Spinal Cord Injury: Distinct Neurite Morphology of DRG Neurons from Mice Expressing Human ApoE3 or ApoE4
Neurotherapeutics
Neurorehabilitation
- Afferent Peripheral Nerve Stimulation for Motor Rehabilitation Controlled by Movement Intention in an EEG-based Brain-Machine Interface
- Describing Movement-related Cortical Dynamics Using Electroencephalography and Diffuse Correlation Spectroscopy
- Impairments in Dynamic Gait Stability are Related to the Deficits in Somatosensory and Cerebellar Involvement in People with Multiple Sclerosis
- Investigating Therapy Participation and Engagement Outcome Measure Reports by Music Therapists and Physical Therapists Co-Treating in Acute Care
Neurovascular Stroke
- Leukemia Inhibitory Factor-loaded Nanoparticles with Enhanced Stability and Anti-Inflammatory Activity for Ischemic Stroke Treatment
- Brain Microvascular Injury and White Matter Disease Provoked by Diabetes-associated Hyperamylinemia
- Cerebrovascular Pathology in Down Syndrome and Alzheimer's Disease
- Activation of the TWEAK/Fn14 Pathway Drives Neuroinflammation After Subarachnoid Hemorrhage
- Cerebral Amyloid Angiopathy and Micrphemorrhages in the Occipital Cortex of Aging Adults with Down Syndrome
- Cerebrovascular and Alzheimer's Disease are Associated with Different Subcortical White Matter Microstructural Damage Mechanisms
- Characterization of Cerebrovascular Changes in the Hyperhomocysteinemia Model of Vascular Dementia
- Impact of Cocaine Use on Acute Ischemic Stroke Patients: Insights from Nationwide Inpatient Sample in the United States
- Inhibition of BMP-Smad1 Signaling and Neural Stem Cell Transplantation for Enhanced Brain Repair from Ischemia-reperfusion Injury
- Neurovascular Damage and Inflammation in the Brains of Nonhuman Primates Fed an Atherogenic Diet
- Translational Evaluation of Acid/Base and Electrolyte Alterations in Rodent Model of Focal Ischemia
Other Therapeutic Areas
- Dose Dense Temozolomide in Patients with Recurrent High Grade Gliomas: The UK Experience
- Inaccuracies in Coding in Neonatal Stroke
- Investigating Potential Mechanisms of Clove Oil (Eugenol) in Model Systems
- Medication Reduction After DBS Placement in Parkinson's Disease
- Neurological Immune Related Adverse Events After Treatment with Immune Checkpoint Inhibitors
- Programming Deep Brain Stimulation in the Globus Pallidus Internus for Treatment of Idiopathic Parkinson's Disease: Experience at the University of KY
- Telemedicine-based, Multidisciplinary-team, Intervention to Reduce Problematic Behaviors of Dementia Patients Residing in Skilled Nursing Facilities
- Using an Adaptive Trial Design to Examine the Safety and Feasibility of Deploying Cell Therapy in Patients with Parkinson's Disease
Memory/Cognition
- APOE, Metabolism and Cognitive Function: An Assessment via Indirect Calorimetry
- Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice
- Targeting P-glycoprotein in a Mouse Model of Alzheimer's Disease: Insights from a Long-Term Study
- Simulating Executive Function Deficits in ADHD Using Artificial Neural Networks