2018 KNI Clinical-Translational Research Symposium Abstracts

• The Triangle of Death of Neurons in Chemotherapy Induced Cognitive Impairment ("Chemobrain")
• Potentially Inappropriate Medication Use and Incident Dementia in Privately-Insured Older Adults
• White Matter Hyperintensity Regression is Associated with Better Executive Function
• Effect of Long-term Dietary Vitamin D3 Supplementation on Cognition in Aging Male and Female F344 Rats
• Origami Paper Folding Intervention Changes Alpha Oscillations Associated with Better Cognitive Ability in Normal Older Adults
• Sex Differences in Brain Activity and Memory Performance Correlates in Healthy Older Adults
• Cognitive Insight in the Stroke Population

• Seizure Prediction with Autonomic Measurements versus Intracranial EEG in Patients with Refractory Epilepsy
• Epileptic Seizures in Aneurysmal Subarachnoid Hemorrhage: Predictive Factors and Utilization of Electroencephalography
• Characterization of Sleep and Seizures in a Knockout Mouse Model of Lafora Disease
• Extrinsic Regulation of Synaptic Connectivity and Neural Circuit Hyper-excitability by Cell Polarity Proteins
• Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Anti-body Enzyme Fusion

• Apomorphine-induced BOLD activations correlate with motor deficits and basal ganglia dysfunction in hemiparkinsonian rhesus macaques
• Benefit of Inpatient Rehabilitation in Patients with Paramyotonia Congenita: A Case Report
• Peripheral Nerve Grafts Implanted Into the Substantia Nigra in Patients with PD During DBS Surgery: 2-year Follow-up Study of Gait Parameters
• Taste Function In early Stage Treated and Untreated Parkinson's Disease
• Diverse Biochemical and Immunoflourescent Characteristics of Proteopathic Alpha-Synuclein in PD and MSA
• Sural Nerve Grafting as a Disease Modifying Therapy for Parkinson's Disease
• Neuro-Avatar: A Reverse Translational model of an Ongoing Cell Therapy Clinical Trial for Parkinson's Disease
• Five-year Review of DBS Plus: A Clinical Trial Platform for Combining Delivery of Investigational Therapeutics with Deep Brain Stimulation Surgery
• Four-week Anti-gravity Treadmill Gait Training in Individuals with Multiple Sclerosis: A Case Series

• Exploring Approaches to Promote Respiratory Motor Plasticity Through Varied and Fixed Interval Intermittent Hypoxia
• A Systematic Review of Closed Head Injury Models of Mild Traumatic Brain Injury in Rodents
• Enhancing Motor Recovery with Brain Stimulation in Spinal Cord Injury
• Aged Astrocytes Maladaptively Contribute to the Neuroinflammatory Milieu Following TBI
• From Paralysis to Regrowth- Inducing Breathing Motor Recovery After Cervical Spinal Cord Injury
• Acute Mitochondrial Impairment Underlies Prolonged Cellular Dysfunction After Repeated Mild Traumatic Brain Injuries
• The Influence of the Microbiome on Brain and Gut Pathology After Traumatic Brain Injury
• A Pharmacologic Neuroprotective Approach to Experimental TBI: Targeting Mitochondria & Lipid Peroxidation-derived Aldehydes
• Neuromodulation Paired With Locomotor Training Improves Muscle Strength After Motor Complete Spinal Cord Injury: A Case Report
• Pioglitazone Maintains Mitochondrial Bioenergetics via Binding to MitoNEET Following Spinal Cord Injury
• Nanoparticle Delivery of miR-146 Altered the Expression of Macrophage/Microglia Makes Genes in Traumatic Injured Rat Brain
• Electrophysiological Signatures of Detecting Malingered Brain Injury

The Effects of a Bacterial Endotoxin LPS: Neuromuscular Junction and Cardiac Function in Drosophilia Melanogaster and Phaenicia Sericata Larvae

Fibroblast Growth Factor 19 Alters Excitability in the Dorsal Motor Nucleus of the Vagus

Effects of TEA and 4-AP on Firing Frequency of Proprioceptive Neurons in Crustaceans

The Effects of a Ketogenic Diet on Behavior and Synaptic Transmission in a Drosophilia Model

The Influence of Endotoxic (LPS) on Primary Sensory Neurons in Crustaceans: Impact on Human Proprioception

Dose-response Relationship of Transcutaneous Spinal Direct Current Stimulation in Healthy Humans: A Proof of Concept Study

Nonpharmacological Regulation of the Ultradian Sleep-Wake Cycle in Mice

Effects of Fibularis Longus Dry Needling on Balance and Spinal Reflex Excitability in Healthy Adults

• Evaluation of Geographic Factors for Rural Patients Needing Access to Mechanical Thrombectomy At a Comprehensive Stroke Center
• Dyshomeostasis of Pancreatic Amylin Provokes Hypoxia and Accelerates Aging
• A Wearable Optical Sensor for Continuous Monitoring of Cerebral Blood Flow in Mice
• Antithrombotic Bridging in Patients with Acute Ischemic Stroke and Atrial Fibrilation
• Peri-Infarct Acid/Base and Electrolyte Alterations in Acute Large Vessel Occlusion Stroke
• The Blood and Clot Thrombectomy Registry and Collaboration (BACTRAC) Protocol: Evaluation of Optimal RNA Extraction and Proteomic Analyses in Stroke
• The Small Peptide ATN-161 as a Novel Potential Therapeutic for Vascular Disease
• A Pilot Study Identifying Brain-targeting Adaptive Immunity in Pediatric ECMO Patients with Acquired Brain Injury
• Development of a Semiautomated Volumetric Quantification Method for Cerebral Microbleed Using T2* Weighted Imaging
• Implementation of an Early Mobilization Protocol in Acute Ischemic Stroke Patients Following Thrombolysis
• Early Mobilization Following Recombinant Tissue Plasminogen Activator Administration and/or Mechanical Thrombectomy Reduces Length of Stay
• Contemporary Seasonal Variations in Transient Ischemic Attack Hospitalizations in the United States: An Update on the Existing Literature

• CSF Amylin – Effect Modifier of the Aβ-AD Relationship
• Analyses of Peripheral Blood Micro RNA Expression in Female Crack-Cocaine Dependents
• Noninvasive Noncontact Speckle Contrast Diffuse Correlation Tomography of Cerebral Blood Flow in Rats
• APOE Genotype Effect on Respiratory Quotient - A Potential Biomarker for Alzheimer's Disease Risk

• Patterns of Care, Operative Morbidity, and Survival of Cranial Chordomas: 10-year Analysis of the NCDB, SEER, and NSQIP Database
• Brain Radiation Necrosis in a State-based Registry
• Gliomatosis Cerebri: Disparities Beyond Molecular Similarities

• Crowdsourcing Health Behavior: Adverse Childhood Experiences, Tobacco Use, and Obesity

• Longer Average Length of Stay Predicts Increased Risk of Readmission, Complications, and Mortality at the Hospital Level in Psychiatric Patients

• A Non-invasive Alternative to Selective Sleep Restriction in Rodents Using Somatosensory Stimulation

• Inflammation and Oxidative Stress in Animal Models of Hydrocephalus

• The Neurocognitive Effects of Exogenous βeta-hydroxybutyrate Administration in Non-clinical and a Clinical MTBI Case Series
• Differential Effects of Non-invasive Brain Stimulation in Chronic Neuropathic Pain: Preliminary Findings of an Ongoing Double-blind Randomized Control

• Quantification of Siaiorrhea Reduction After Unilateral Parotid Electron Beam Radiotherapy in Debilitating Neurological Disorders
• Changes in Microglia Across the Lifespan
• Subset of Gene Expression Profiles in Human Post-mortem Brain Aging and AD are Robust, Concordant, and Show Exaggerated Changes in Female AD Subjects
• Flow Cytometry Distinguishes Synaptosome Populations Containing a Progression of AD Pathologic Markers in Human Autopsy Brain and Tg Animal Model

• Brain Blast
• Intra-articular CGRP Plays a Key Role In Development of Osteoarthritis
• Retrospective Summary of a Decade of Experience with Pre-Surgical Functional MR Imaging
• Retrospective Analysis of Changes in Drug Use Patterns Between 2012-2017 in Patients Presenting with Neurosurgical Problems
• Meditation and Its Impact on Psychomotor Vigilance
• Pilot Study of Burnout, Satisfaction, and Wellness Among Residents in Neurology and Psychiatry