Institutional Animal Care and Use Committee IACUC
The University of Kentucky Institutional Animal Care and Use Committee (IACUC) supports the Division of Laboratory Animal Resources as a fully accredited program with the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC), International, a voluntary peer review organization since 1966.
The IACUC, reporting to the University’s Associate Vice President for Research Integrity, provides leadership and oversight of IACUC functions related to animal care and use at the University of Kentucky (UK). A major area of responsibility includes playing a central role in ensuring the ethical and responsible care and use of animals in research, teaching and testing endeavors in congruence with the applicable federal laws and guidelines as well as institutional and AAALAC accreditation standards. Implicit in this role is a continual assessment of operational practices with the intent of facilitating the research endeavors of UK faculty using animal models while upholding high standards of animal care and use and ensuring all parties (IACUC members and investigators alike) understand the objectives and standards and work to apply them in a consistent and reasonable manner.
Frequently Asked Questions
What are the functions of the IACUC?
Functions of the IACUC include: review, at least once every six months, the University of Kentucky’s program for humane care and use of animals; inspect, at least once every six months, all of the animal facilities and locations where animals are used; prepare reports of its evaluations and submit the reports to the Institutional Official; review, and, if warranted, investigate concerns involving the care and use of animals; make recommendations to the Institutional Official regarding any aspect of the research facility's animal program and facilities; review and approve, require modifications in (to secure approval), or withhold approval of proposed activities and significant changes related to the care and use of animals; be authorized to suspend an activity involving animals.
What is the composition of UK’s IACUC?
UK’s IACUC currently consists of an IACUC Chair, Vice Chair, Attending Veterinarian, Scientists, Non-Scientists, a community member and several alternates.
Scientists come from several different departments on campus including researchers in the Colleges of Medicine, Arts & Sciences, Engineering and Agriculture. Other members are from DLAR, USDA-ARS, Library Sciences, and Environmental Health and Safety. Ex-officio members include those with expertise in administration, statistics, pharmacy, legal services, and facilities management.
What is the difference between the AV and the Division of Laboratory Animal Resources (DLAR) and the IACUC?
The AV ensures that animals receive adequate veterinary care and oversees the adequacy of other aspects of animal care and use.
DLAR is a service unit under the Office of the Vice President for Research. DLAR supports the biomedical research community at UK by providing the highest quality veterinary services and humane care and treatment to the animals under their care. DLAR serves as a resource for knowledge and technical expertise for researchers. DLAR has been continuously accredited by the Association for the Assessment and Accreditation for Laboratory Animal Care, International (AAALAC, International).
The IACUC is charged with oversight and routine evaluation of the Program of Animal Care and Use. This includes all the activities as listed above (see FAQ 2)
In summary, the Program of Animal Care and Use requires the collaborative effort of the IO, the AV, the IACUC, as well as that of DLAR to ensure it functions effectively and in compliance with the law and other regulations.
How long does it take to get a protocol approved by the IACUC?
The IACUC strives to review protocols in a timely fashion. Protocol approval is granted only after all required items (training, OHSP clearance, IBC/Radiation safety, etc.) have been completed and all reviewer questions have been satisfied. As a general guideline, protocols should be submitted to our office 2 months before the anticipated date of approval. For additional information see Guidance on Protocol Submission Deadlines.
IACUC Leadership
M. Paul Murphy
IACUC Chair
michael.murphy@uky.edu
Kyle McLeod
Vice Chair
kyle.mcleod@uky.edu