Nearly three decades after first discovering the tumor-suppressing Par-4 “super gene” that has been shown to kill cancer cells, a team of researchers at the University of Kentucky Markey Cancer Center is now learning about its role in preventing obesity.
Through reconstructing an evolutionary history a UK-led team, in collaboration with researchers from Mexico, have discovered that genetic differences between axolotls and other salamanders in their region of Mexico were almost indistinguishable.
Research published in Nature Regenerative Medicine shows a unique ability of this mammalian species to grow new blood vessels and reduce cardiac tissue damage after a heart attack.
A recently released paper from the Department of Physiology and Sanders-Brown Center on Aging (SBCoA) suggests that genetics can influence response to Alzheimer’s disease pathology.
University of Kentucky College of Medicine researchers were part of a recently published study giving insight into how limb development evolved in vertebrates.
The research team will take a closer look at how the muscle weakness associated with Marfan syndrome leads to problems with hip joint muscle function, muscle morphology and gait mechanics. The exact association of these factors with the onset of hip joint pain and cartilage degeneration is unknown and of particular interest to the researchers.
Emilia Galperin, a Kentucky College of Medicine researcher, has been awarded $1.9 million to continue research examining molecular pathogenesis of Noonan-like syndrome.