Research News

From left, David Higdon, with his children Luke and Ashley, and wife Tonya, enjoys a family trip to Scotland

Ky. attorney defies brain cancer odds through Markey clinical trial

May 15, 2025, 7:26 AM

Following surgery to remove a tumor from his brain, David Higdon was offered the opportunity to participate in an NIH-funded clinical trial.

Mark Evers outside a lab at the Healthy Kentucky Research Building

Research Advancing Kentucky: Propelling the science behind cancer care

May 2, 2025, 9:00 AM

Researchers at the University of Kentucky play an important role in advancing the health, well-being and future of our Commonwealth. Much of that work is done with support from the National Institutes of Health (NIH). That support allows our researchers to find answers to many of the critical health issues facing Kentuckians.

3D rendering of neurotensin neurotransmitter peptide molecule

Markey research team discovers gut hormone’s role in fatty liver disease

Apr 28, 2025, 3:13 PM

UK Markey Cancer Center researchers have identified a mechanism by which a gut hormone contributes to fatty liver disease, offering potential new targets for treating the common condition.

Research Advancing Kentucky: Providing hope to pediatric cancer patients

Apr 28, 2025, 6:33 AM

With NIH support, John D’Orazio combines his research with active clinical practice, treating pediatric patients with cancer and blood disorders.

Markey reaches 10,000 patient milestone in national cancer research network

Apr 22, 2025, 6:24 AM

The UK Markey Cancer Center has enrolled its 10,000th patient in the Oncology Research Information Exchange Network (ORIEN) since joining the alliance in 2017.

Jinghui Liu and Xiaoqi Liu at the 2023 AACR conference

Markey researchers to present groundbreaking cancer findings at AACR meeting

Apr 21, 2025, 2:54 PM

At the annual gathering of cancer experts, the UK Markey Cancer Center team will present studies with the potential to significantly transform cancer care.

Science Signaling Vol. 18, Issue 878 cover

UK study reveals key mechanism behind prostate cancer drug resistance, potential new treatment strategy

Apr 10, 2025, 7:31 AM

A team of UK Markey Cancer Center researchers has found the mechanism that grants prostate cancer resistance to enzalutamide, a frequently used drug.

Plant-based coffee yields promising results in Markey ovarian cancer trial

Apr 4, 2025, 7:07 AM

Recent research shows that a commercially available decaffeinated coffee product containing a controlled dose of Artemisia annua may have anti-cancer properties.

UK researchers explore the high incidence of colorectal cancer in Appalachian Kentucky

Apr 2, 2025, 7:24 AM

Researchers focused on analyzing samples from patients diagnosed with colon adenocarcinoma and looking at characteristics that could explain disparities in cancer outcomes in Kentucky.

Markey researchers help discover diet, lung cancer link

Mar 31, 2025, 7:31 AM

Researchers from Markey Cancer Center have found that a “Western diet” increases glycogen levels in the lungs, accelerating tumor growth and worsening patient outcomes.

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